| Tissue Specificity | Ubiquitously expressed. |
| Post Translational Modifications | Phosphorylated by CDK1. May regulate its subcellular location. |
| Function | Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates. |
| Protein Name | Cell Division Cycle-Associated Protein 2Recruits Pp1 Onto Mitotic Chromatin At Anaphase ProteinRepo-Man |
| Cellular Localisation | NucleusExcluded From The NucleolusPresent In Nucleoplasm Throughout The G1S And G2 Stages Of The Cell CycleDuring M PhaseIt Becomes Diffuse Throughout The Cell As The Nuclear Membrane Breaks DownAnd Faintly Accumulates Later On Metaphase ChromatinAs The Cell Progresses To AnaphaseIt Accumulates On Chromatin |
| Alternative Antibody Names | Anti-Cell Division Cycle-Associated Protein 2 antibodyAnti-Recruits Pp1 Onto Mitotic Chromatin At Anaphase Protein antibodyAnti-Repo-Man antibodyAnti-CDCA2 antibody |
Information sourced from Uniprot.org
