• Western blot analysis of lysate from MCF7 cells, using LILRA4 Antibody.
  • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
  • Western blot analysis of MCF7 cells using CD85g Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-LILRA4 antibody (391-440 aa) (STJ96623)

SKU:
STJ96623

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Leukocyte immunoglobulin-like receptor subfamily A member 4 (391-440 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LILRA4
Gene ID: 23547
Uniprot ID: LIRA4_HUMAN
Immunogen Region: 391-440 aa
Specificity: CD85g Polyclonal Antibody detects endogenous levels of CD85g protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human LILRA4 at the amino acid range 391-440
Function Functions coreceptor to limit the innate immune responses to viral infections.signaling occurs via FCER1G. Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades. Down-regulates interferon production in response to interaction with BST2 on HIV-1 infected cells. Activates a signaling cascade in complex with FCER1G that results in phosphorylation of Src family and Syk kinases and thereby triggers mobilization of intracellular Ca(2+). Does not interfere with the differentiation of plasmacytoid dendritic cells into antigen-presenting cells.
Protein Name Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 4
Cd85 Antigen-Like Family Member G
Immunoglobulin-Like Transcript 7
Ilt-7
Cd Antigen Cd85g
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 4 antibody
Anti-Cd85 Antigen-Like Family Member G antibody
Anti-Immunoglobulin-Like Transcript 7 antibody
Anti-Ilt-7 antibody
Anti-Cd Antigen Cd85g antibody
Anti-LILRA4 antibody
Anti-ILT7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance