Anti-CD85a/LILRB3 antibody [A1] (STJA0027757)

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STJA0027757
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Host: Human
Applications: ELISA/FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Human monoclonal antibody anti-Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3 is suitable for use in ELISA and Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : A1
Conjugation: Unconjugated
Isotype: IgG1L
Formulation: 0.01M PBS, pH 7.4.
Purification: Protein A/G purified from cell culture supernatant.
Concentration: 2 mg/ml
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: LILRB3
Gene ID: 102725035/107987462
Uniprot ID: LIRB3_HUMAN
Post Translational Modifications Phosphorylated on tyrosine residues by LYN. Phosphorylation at Tyr-595 and Tyr-625 is important for interaction with PTPN6/SHP-1 and PTPN11/SHP-2.
Function May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
Protein Name Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3
Lir-3
Leukocyte Immunoglobulin-Like Receptor 3
Cd85 Antigen-Like Family Member A
Immunoglobulin-Like Transcript 5
Ilt-5
Monocyte Inhibitory Receptor Hl9
Cd Antigen Cd85a
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3 antibody
Anti-Lir-3 antibody
Anti-Leukocyte Immunoglobulin-Like Receptor 3 antibody
Anti-Cd85 Antigen-Like Family Member A antibody
Anti-Immunoglobulin-Like Transcript 5 antibody
Anti-Ilt-5 antibody
Anti-Monocyte Inhibitory Receptor Hl9 antibody
Anti-Cd Antigen Cd85a antibody
Anti-LILRB3 antibody
Anti-ILT5 antibody
Anti-LIR3 antibody

Information sourced from Uniprot.org

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