Anti-CD45/PTPRC antibody [SAA0570] {FITC} (STJA0028119)

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STJA0028119
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: FC
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal antibody anti-Receptor-Type Tyrosine-Protein Phosphatase C is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : SAA0570
Conjugation: FITC
Isotype: VHH, mFc (IgG2a)
Formulation: 0.01M PBS, pH 7.4, 02% BSA, 0.05% Proclin 300
Purification: Purified
Concentration: 05 mg/mL
Storage Instruction: Store at 4°C for 12 months Protect from light Do not freeze
Gene Symbol: Ptprc
Gene ID: 19264
Uniprot ID: PTPRC_MOUSE
Function Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
Protein Name Receptor-Type Tyrosine-Protein Phosphatase C
Leukocyte Common Antigen
L-Ca
Lymphocyte Antigen 5
Ly-5
T200
Cd Antigen Cd45
Database Links Reactome: R-MMU-202427
Reactome: -MMU-416700
Reactome: -MMU-6798695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Membrane Raft
Synapse
Colocalized With Dpp4 In Membrane Rafts
Alternative Antibody Names Anti-Receptor-Type Tyrosine-Protein Phosphatase C antibody
Anti-Leukocyte Common Antigen antibody
Anti-L-Ca antibody
Anti-Lymphocyte Antigen 5 antibody
Anti-Ly-5 antibody
Anti-T200 antibody
Anti-Cd Antigen Cd45 antibody
Anti-Ptprc antibody
Anti-Ly-5 antibody

Information sourced from Uniprot.org

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