Host: |
Rabbit |
Applications: |
WB/IHC-P/IF/ICC/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Monoclonal |
Clone ID: |
SRM |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.09% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:7500-1:15000IHC-P:1:200-1:800IF/ICC:1:1600-1:6400ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Gene Symbol: |
Cd38 |
Gene ID: |
12494 |
Uniprot ID: |
CD38_MOUSE |
Immunogen Region: |
45-304 aa |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 45-304 of mouse CD38 (NP_031672.2). |
Immunogen Sequence: |
LRPRSLLVWTGEPTTKHFSD IFLGRCLIYTQILRPEMRDQ NCQEILSTFKGAFVSKNPCN ITREDYAPLVKLVTQTIPCN KTLFWSKSKHLAHQYTWIQG KMFTLEDTLLGYIADDLRWC GDPSTSDMNYVSCPHWSENC PNNPITVFWKVISQKFAEDA CGVVQVMLNGSLREPFYKNS TFGSVEVFSLDPNKVHKLQA WVMHDIEGASSNACSSSSLN ELKMIVQKRNMIFACVDNY |
Function | Synthesizes the second messengers cyclic ADP-ribose (cADPR) and nicotinate-adenine dinucleotide phosphate (NAADP), the former a second messenger for glucose-induced insulin secretion, the latter a Ca(2+) mobilizer. Also has cADPR hydrolase activity. |
Protein Name | Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 12'-Phospho-Adp-Ribosyl Cyclase2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase2'-Phospho-Cyclic-Adp-Ribose TransferaseAdp-Ribosyl Cyclase 1Adprc 1Cyclic Adp-Ribose Hydrolase 1Cadpr Hydrolase 1I-19Nim-R5 AntigenCd Antigen Cd38 |
Database Links | Reactome: R-MMU-196807 |
Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
Alternative Antibody Names | Anti-Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 antibodyAnti-2'-Phospho-Adp-Ribosyl Cyclase antibodyAnti-2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase antibodyAnti-2'-Phospho-Cyclic-Adp-Ribose Transferase antibodyAnti-Adp-Ribosyl Cyclase 1 antibodyAnti-Adprc 1 antibodyAnti-Cyclic Adp-Ribose Hydrolase 1 antibodyAnti-Cadpr Hydrolase 1 antibodyAnti-I-19 antibodyAnti-Nim-R5 Antigen antibodyAnti-Cd Antigen Cd38 antibodyAnti-Cd38 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance