Function | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
Protein Name | Programmed Cell Death 1 Ligand 2Pd-1 Ligand 2Pd-L2Pdcd1 Ligand 2Programmed Death Ligand 2Butyrophilin B7-DcB7-DcCd Antigen Cd273 |
Database Links | Reactome: R-HSA-389948 |
Cellular Localisation | Isoform 3: SecretedIsoform 2: Endomembrane SystemSingle-Pass Type I Membrane ProteinIsoform 1: Cell Membrane |
Alternative Nanobody Names | Anti-Programmed Cell Death 1 Ligand 2 nanobodyAnti-Pd-1 Ligand 2 nanobodyAnti-Pd-L2 nanobodyAnti-Pdcd1 Ligand 2 nanobodyAnti-Programmed Death Ligand 2 nanobodyAnti-Butyrophilin B7-Dc nanobodyAnti-B7-Dc nanobodyAnti-Cd Antigen Cd273 nanobodyAnti-PDCD1LG2 nanobodyAnti-B7DC nanobodyAnti-CD273 nanobodyAnti-PDCD1L2 nanobodyAnti-PDL2 nanobody |
Information sourced from Uniprot.org