Anti-CD273/PD-L2/PDCD1LG2 nanobody [SAA1281] (STJN000298)

SKU:
STJN000298
£378.50 - £1,632.50
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Host: Alpaca
Applications: ELISA/FC/SPR
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Programmed Cell Death 1 Ligand 2 is suitable for use in ELISA, Flow Cytometry and SPR research applications.
Clonality : Monoclonal
Clone ID : SAA1281
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: PDCD1LG2
Gene ID: 80380
Uniprot ID: PD1L2_HUMAN
Function Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Protein Name Programmed Cell Death 1 Ligand 2
Pd-1 Ligand 2
Pd-L2
Pdcd1 Ligand 2
Programmed Death Ligand 2
Butyrophilin B7-Dc
B7-Dc
Cd Antigen Cd273
Database Links Reactome: R-HSA-389948
Cellular Localisation Isoform 3: Secreted
Isoform 2: Endomembrane System
Single-Pass Type I Membrane Protein
Isoform 1: Cell Membrane
Alternative Nanobody Names Anti-Programmed Cell Death 1 Ligand 2 nanobody
Anti-Pd-1 Ligand 2 nanobody
Anti-Pd-L2 nanobody
Anti-Pdcd1 Ligand 2 nanobody
Anti-Programmed Death Ligand 2 nanobody
Anti-Butyrophilin B7-Dc nanobody
Anti-B7-Dc nanobody
Anti-Cd Antigen Cd273 nanobody
Anti-PDCD1LG2 nanobody
Anti-B7DC nanobody
Anti-CD273 nanobody
Anti-PDCD1L2 nanobody
Anti-PDL2 nanobody

Information sourced from Uniprot.org