Anti-CD16b/FCGR3B nanobody [C28] (STJN000595)

Anti-CD16b/FCGR3B nanobody [C28] (STJN000595)

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STJN000595
£378.50 - £1,632.50
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Host: Alpaca
Applications: ELISA/FuncS
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B is suitable for use in ELISA and FuncS research applications.
Clonality : Monoclonal
Clone ID : C28
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: FCGR3B
Gene ID: 2215
Uniprot ID: FCG3B_HUMAN
Post Translational Modifications Glycosylated. Glycosylation plays an inhibitory role in the interaction with IgG3. The soluble form is produced by a proteolytic cleavage.
Function Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Protein Name Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B
Fc-Gamma Riii-Beta
Cd16-I
Fc-Gamma Riii
Fc-Gamma Riiib
Fcriii
Fcriiib
Fcr-10
Igg Fc Receptor Iii-1
Cd Antigen Cd16b
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Secreted After Cleavage
Alternative Nanobody Names Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B nanobody
Anti-Fc-Gamma Riii-Beta nanobody
Anti-Cd16-I nanobody
Anti-Fc-Gamma Riii nanobody
Anti-Fc-Gamma Riiib nanobody
Anti-Fcriii nanobody
Anti-Fcriiib nanobody
Anti-Fcr-10 nanobody
Anti-Igg Fc Receptor Iii-1 nanobody
Anti-Cd Antigen Cd16b nanobody
Anti-FCGR3B nanobody
Anti-CD16B nanobody
Anti-FCG3 nanobody
Anti-FCGR3 nanobody
Anti-IGFR3 nanobody

Information sourced from Uniprot.org

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