• Western blot analysis of extracts of mouse brain, using CAPNS2 antibody (STJ114270) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-CAPNS2 antibody (1-100) (STJ114270)

SKU:
STJ114270

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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CAPNS2 (1-100) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CAPNS2
Gene ID: 84290
Uniprot ID: CPNS2_HUMAN
Immunogen Region: 1-100
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CAPNS2 (NP_115706.1).
Immunogen Sequence: MFLAKALLEGADRGLGEALG GLFGGGGQRREGGGRNIGGI VGGIVNFISEAAAAQYTPEP PPTQQHFTSVEASESEEVRR FRQQFTQLAGPDMEVGATDL
Function Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.
Protein Name Calpain Small Subunit 2
Css2
Calcium-Dependent Protease Small Subunit 2
Database Links Reactome: R-HSA-1474228
Reactome: R-HSA-8862803
Cellular Localisation Cytoplasm
Cell Membrane
Translocates To The Plasma Membrane Upon Calcium Binding
Alternative Antibody Names Anti-Calpain Small Subunit 2 antibody
Anti-Css2 antibody
Anti-Calcium-Dependent Protease Small Subunit 2 antibody
Anti-CAPNS2 antibody

Information sourced from Uniprot.org

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