| Host: |
Rabbit |
| Applications: |
WB/IF/ICC/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CAMSAP1 |
| Gene ID: |
157922 |
| Uniprot ID: |
CAMP1_HUMAN |
| Immunogen Region: |
350-650 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 350-650 of human CAMSAP1 (NP_056262.3). |
| Immunogen Sequence: |
KTVLHQKSSRPPVPISNATK RSFLGSPAAGTLAELQPPVQ LPAEGCHRHYLHPEEPEYLG KGTAAFSPSHPLLPLRQKQQ KSIQGEDIPDQRHRSNSLTR VDGQPRGAAIAWPEKKTRPA SQPTPFALHHAASCEVDPSS GDSISLARSISKDSLASNIV NLTPQNQPHPTATKSHGKSL LSNVSIEDEEEELVAIVRAD VVPQQADPEFPRASPRALGL TANARSPQGQLDTSESKPD |
| Function | Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization. Specifically recognizes growing microtubule minus-ends and stabilizes microtubules. Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization. In contrast to CAMSAP2 and CAMSAP3, tracks along the growing tips of minus-end microtubules without significantly affecting the polymerization rate: binds at the very tip of the microtubules minus-end and acts as a minus-end tracking protein (-TIP) that dissociates from microtubules after allowing tubulin incorporation. Through interaction with spectrin may regulate neurite outgrowth. |
| Protein Name | Calmodulin-Regulated Spectrin-Associated Protein 1 |
| Cellular Localisation | CytoplasmCytoskeletonAssociates With The Minus-End Of MicrotubulesIn Contrast To Camsap2 And Camsap3Does Not Form Stretches Of Decorated Microtubule Minus-Ends |
| Alternative Antibody Names | Anti-Calmodulin-Regulated Spectrin-Associated Protein 1 antibodyAnti-CAMSAP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
