| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CALY |
| Gene ID: | 50632 |
| Uniprot ID: | CALY_HUMAN |
| Immunogen Region: | 1-87 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-87 of human CALY (NP_056537.1). |
| Immunogen Sequence: | MVKLGCSFSGKPGKDPGDQD GAAMDSVPLISPLDISQLQP PLPDQVVIKTQTEYQLSSPD QQNFPDLEGQRLNCSHPEEG RRLPTAR |
| Tissue Specificity | Expressed in the pyramidal cells of the prefrontal cortex, in hypothalamus and in caudate nucleus. No expression in spleen. Up-regulated in the prefrontal cortex of schizophrenic patients with nearly twice the levels of non-schizophrenics. |
| Post Translational Modifications | Glycosylated. |
| Function | Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis. |
| Protein Name | Neuron-Specific Vesicular Protein Calcyon |
| Cellular Localisation | Cytoplasmic Vesicle MembraneSingle-Pass Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Neuron-Specific Vesicular Protein Calcyon antibodyAnti-CALY antibodyAnti-DRD1IP antibody |
Information sourced from Uniprot.org