• Western blot analysis of extracts of various cell lines, using CACNG4 antibody (STJ116053) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-CACNG4 antibody (208-327) (STJ116053)

SKU:
STJ116053

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CACNG4 (208-327) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CACNG4
Gene ID: 27092
Uniprot ID: CCG4_HUMAN
Immunogen Region: 208-327
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 208-327 of human CACNG4 (NP_055220.1).
Immunogen Sequence: EKNKELRFKTKREFLKASSS SPYARMPSYRYRRRRSRSSS RSTEASPSRDVSPMGLKITG AIPMGELSMYTLSREPLKVT TAASYSPDQEASFLQVHDFF QQDLKEGFHVSMLNRRTTPV
Tissue Specificity Detected in heart left ventricle.
Function Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.
Protein Name Voltage-Dependent Calcium Channel Gamma-4 Subunit
Neuronal Voltage-Gated Calcium Channel Gamma-4 Subunit
Transmembrane Ampar Regulatory Protein Gamma-4
Tarp Gamma-4
Database Links Reactome: R-HSA-112308
Reactome: R-HSA-399719
Reactome: R-HSA-5576892
Reactome: R-HSA-5576893
Reactome: R-HSA-5682910
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Voltage-Dependent Calcium Channel Gamma-4 Subunit antibody
Anti-Neuronal Voltage-Gated Calcium Channel Gamma-4 Subunit antibody
Anti-Transmembrane Ampar Regulatory Protein Gamma-4 antibody
Anti-Tarp Gamma-4 antibody
Anti-CACNG4 antibody

Information sourced from Uniprot.org

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