Western blot analysis of various lysates using CACNA2D1 Rabbit polyclonal antibody (STJ117455) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5S.

Anti-CACNA2D1 antibody (550-800) (STJ117455)

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STJ117455
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:200-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CACNA2D1
Gene ID: 781
Uniprot ID: CA2D1_HUMAN
Immunogen Region: 550-800
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 550-800 of human CACNA2D1 (NP_000713.2).
Immunogen Sequence: DIKVEIRNKMIDGESGEKTF RTLVKSQDERYIDKGNRTYT WTPVNGTDYSLALVLPTYSF YYIKAKLEETITQARSKKGK MKDSETLKPDNFEESGYTFI APRDYCNDLKISDNNTEFLL NFNEFIDRKTPNNPSCNADL INRVLLDAGFTNELVQNYWS KQKNIKGVKARFVVTDGGIT RVYPKEAGENWQENPETYED SFYKRSLDNDNYVFTAPYFN KSGPGAYESGIMVSKAVEI
Tissue Specificity Isoform 1 is expressed in skeletal muscle. Isoform 2 is expressed in the central nervous system. Isoform 2, isoform 4 and isoform 5 are expressed in neuroblastoma cells. Isoform 3, isoform 4 and isoform 5 are expressed in the aorta.
Post Translational Modifications Proteolytically processed into subunits alpha-2-1 and delta-1 that are disulfide-linked.
Function The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling.
Protein Name Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-1
Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-1 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-1 - Voltage-Dependent Calcium Channel Subunit Delta-1
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Membrane
Alternative Antibody Names Anti-Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-1 antibody
Anti-Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-1 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-1 - Voltage-Dependent Calcium Channel Subunit Delta-1 antibody
Anti-CACNA2D1 antibody
Anti-CACNL2A antibody
Anti-CCHL2A antibody
Anti-MHS3 antibody

Information sourced from Uniprot.org

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