• Western blot analysis of lysates from A549 cells, using CACNA1H Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of the lysates from HeLa cells using CACNA1H antibody.
  • Western blot analysis of various cells using T-type Ca++ CP Alpha 1H Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Anti-CACNA1H antibody (462-511 aa) (STJ96138)

SKU:
STJ96138

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Voltage-dependent T-type calcium channel subunit alpha-1H (462-511 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CACNA1H
Gene ID: 8912
Uniprot ID: CAC1H_HUMAN
Immunogen Region: 462-511 aa
Specificity: T-type Ca++ CP Alpha 1H Polyclonal Antibody detects endogenous levels of T-type Ca++ CP Alpha 1H protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CACNA1H at the amino acid range 462-511
Post Translational Modifications In response to raising of intracellular calcium, the T-type channels are activated by CaM-kinase II.
Function Voltage-sensitive calcium channel that gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group. A particularity of this type of channel is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle (Probable). They may also be involved in the modulation of firing patterns of neurons. In the adrenal zona glomerulosa, participates in the signaling pathway leading to aldosterone production in response to either AGT/angiotensin II, or hyperkalemia.
Protein Name Voltage-Dependent T-Type Calcium Channel Subunit Alpha-1h
Low-Voltage-Activated Calcium Channel Alpha1 3.2 Subunit
Voltage-Gated Calcium Channel Subunit Alpha Cav3.2
Database Links Reactome: R-HSA-419037
Reactome: R-HSA-445355
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Interaction With Stac Increases Expression At The Cell Membrane
Alternative Antibody Names Anti-Voltage-Dependent T-Type Calcium Channel Subunit Alpha-1h antibody
Anti-Low-Voltage-Activated Calcium Channel Alpha1 3.2 Subunit antibody
Anti-Voltage-Gated Calcium Channel Subunit Alpha Cav3.2 antibody
Anti-CACNA1H antibody

Information sourced from Uniprot.org

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