| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BTBD1 |
| Gene ID: | 53339 |
| Uniprot ID: | BTBD1_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human BTBD1 (NP_079514.1). |
| Immunogen Sequence: | CDGTANTFRVMFKEPIEILP NVCYTACATLKGPDSHYGTK GLKKVVHETPAASKTVFFFF SSPGNNNGTSIEDGQIPEII FYT |
| Tissue Specificity | Ubiquitous.highest levels in testes, heart and skeletal muscle. |
| Function | Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to regulate expression levels and/or subnuclear distribution of TOP1, via an unknown mechanism. May play a role in mesenchymal differentiation where it promotes myogenic differentiation and suppresses adipogenesis. |
| Protein Name | Btb/Poz Domain-Containing Protein 1 Hepatitis C Virus Ns5a-Transactivated Protein 8 Hcv Ns5a-Transactivated Protein 8 |
| Database Links | Reactome: R-HSA-8951664 Reactome: R-HSA-983168 |
| Cellular Localisation | Cytoplasm Localizes To Punctate Or Elongated Cytoplasmic Bodies |
| Alternative Antibody Names | Anti-Btb/Poz Domain-Containing Protein 1 antibody Anti-Hepatitis C Virus Ns5a-Transactivated Protein 8 antibody Anti-Hcv Ns5a-Transactivated Protein 8 antibody Anti-BTBD1 antibody Anti-C15orf1 antibody Anti-NS5ATP8 antibody |
Information sourced from Uniprot.org