Anti-BTBD1 antibody (C-Term) (STJ117355)

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STJ117355
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BTBD1
Gene ID: 53339
Uniprot ID: BTBD1_HUMAN
Immunogen Region: C-Term
Specificity: A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human BTBD1 (NP_079514.1).
Immunogen Sequence: CDGTANTFRVMFKEPIEILP NVCYTACATLKGPDSHYGTK GLKKVVHETPAASKTVFFFF SSPGNNNGTSIEDGQIPEII FYT
Tissue Specificity Ubiquitous.highest levels in testes, heart and skeletal muscle.
Function Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to regulate expression levels and/or subnuclear distribution of TOP1, via an unknown mechanism. May play a role in mesenchymal differentiation where it promotes myogenic differentiation and suppresses adipogenesis.
Protein Name Btb/Poz Domain-Containing Protein 1
Hepatitis C Virus Ns5a-Transactivated Protein 8
Hcv Ns5a-Transactivated Protein 8
Database Links Reactome: R-HSA-8951664
Reactome: R-HSA-983168
Cellular Localisation Cytoplasm
Localizes To Punctate Or Elongated Cytoplasmic Bodies
Alternative Antibody Names Anti-Btb/Poz Domain-Containing Protein 1 antibody
Anti-Hepatitis C Virus Ns5a-Transactivated Protein 8 antibody
Anti-Hcv Ns5a-Transactivated Protein 8 antibody
Anti-BTBD1 antibody
Anti-C15orf1 antibody
Anti-NS5ATP8 antibody

Information sourced from Uniprot.org