Tissue Specificity | Ubiquitous.highest levels in testes, heart and skeletal muscle. |
Function | Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to regulate expression levels and/or subnuclear distribution of TOP1, via an unknown mechanism. May play a role in mesenchymal differentiation where it promotes myogenic differentiation and suppresses adipogenesis. |
Protein Name | Btb/Poz Domain-Containing Protein 1Hepatitis C Virus Ns5a-Transactivated Protein 8Hcv Ns5a-Transactivated Protein 8 |
Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
Cellular Localisation | CytoplasmLocalizes To Punctate Or Elongated Cytoplasmic Bodies |
Alternative Antibody Names | Anti-Btb/Poz Domain-Containing Protein 1 antibodyAnti-Hepatitis C Virus Ns5a-Transactivated Protein 8 antibodyAnti-Hcv Ns5a-Transactivated Protein 8 antibodyAnti-BTBD1 antibodyAnti-C15orf1 antibodyAnti-NS5ATP8 antibody |
Information sourced from Uniprot.org