• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using BCOR Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from COLO cells, using BCOR Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using BCoR Polyclonal Antibody diluted at 1：500 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-BCOR antibody (1231-1280 aa) (STJ91845)

SKU:
STJ91845

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-BCL-6 corepressor (1231-1280 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: BCOR
Gene ID: 54880
Uniprot ID: BCOR_HUMAN
Immunogen Region: 1231-1280 aa
Specificity: BCoR Polyclonal Antibody detects endogenous levels of BCoR protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human BCOR at the amino acid range 1231-1280
Function Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A.impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells.the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).
Protein Name Bcl-6 Corepressor
Bcor
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Bcl-6 Corepressor antibody
Anti-Bcor antibody
Anti-BCOR antibody
Anti-KIAA1575 antibody

Information sourced from Uniprot.org

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