| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-BCAM (352-547) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
BCAM |
| Gene ID: |
4059 |
| Uniprot ID: |
BCAM_HUMAN |
| Immunogen Region: |
352-547 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 352-547 of human CD239/CD239/BCAM (NP_005572.2). |
| Immunogen Sequence: |
KTLELRVAYLDPLELSEGKV LSLPLNSSAVVNCSVHGLPT PALRWTKDSTPLGDGPMLSL SSITFDSNGTYVCEASLPTV PVLSRTQNFTLLVQGSPELK TAEIEPKADGSWREGDEVTL ICSARGHPDPKLSWSQLGGS PAEPIPGRQGWVSSSLTLKV TSALSRDGISCEASNPHGNK RHVFHFGTVSPQTSQA |
| Tissue Specificity | Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls. |
| Post Translational Modifications | Epinephrine-stimulated phosphorylation of Ser-621 by PKA enhances adhesion to laminin. |
| Function | Laminin alpha-5 receptor. May mediate intracellular signaling. |
| Protein Name | Basal Cell Adhesion MoleculeAuberger B AntigenB-Cam Cell Surface GlycoproteinF8/G253 AntigenLutheran AntigenLutheran Blood Group GlycoproteinCd Antigen Cd239 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Basal Cell Adhesion Molecule antibodyAnti-Auberger B Antigen antibodyAnti-B-Cam Cell Surface Glycoprotein antibodyAnti-F8/G253 Antigen antibodyAnti-Lutheran Antigen antibodyAnti-Lutheran Blood Group Glycoprotein antibodyAnti-Cd Antigen Cd239 antibodyAnti-BCAM antibodyAnti-LU antibodyAnti-MSK19 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
