Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-ATP13A1 (880-960) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ATP13A1 |
Gene ID: |
57130 |
Uniprot ID: |
AT131_HUMAN |
Immunogen Region: |
880-960 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 880-960 of human ATP13A1 (NP_065143.2). |
Immunogen Sequence: |
ALLANAPERVVERRRRPRDS PTLSNSGIRATSRTAKQRSG LPPSEEQPTSQRDRLSQVLR DLEDESTPIVKLGDASIAAP F |
Function | Endoplasmic reticulum translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum. Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane. Specifically binds mitochondrial tail-anchored transmembrane proteins: has an atypically large substrate-binding pocket that recognizes and binds moderately hydrophobic transmembranes with short hydrophilic lumenal domains. |
Protein Name | Endoplasmic Reticulum Transmembrane Helix TranslocaseEndoplasmic Reticulum P5a-Atpase |
Database Links | Reactome: R-HSA-936837 |
Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Endoplasmic Reticulum Transmembrane Helix Translocase antibodyAnti-Endoplasmic Reticulum P5a-Atpase antibodyAnti-ATP13A1 antibodyAnti-ATP13A antibodyAnti-KIAA1825 antibodyAnti-CGI-152 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance