Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ATCAY |
Gene ID: |
85300 |
Uniprot ID: |
ATCAY_HUMAN |
Immunogen Region: |
1-105 |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human ATCAY (NP_149053.1). |
Immunogen Sequence: |
MGTTEATLRMENVDVKEEWQ DEDLPRPLPEETGVELLGSP VEDTSSPPNTLNFNGAHRKR KTLVAPEINISLDQSEGSLL SDDFLDTPDDLDINVDDIET PDETD |
Post Translational Modifications | Cleaved by CASP3 and CASP7. The potential C-terminal product released by CASP3 cleavage may inhibit the ERK signaling pathway through MAP2K2. May be ubiquitinated by STUB1. |
Function | Functions in the development of neural tissues, particularly the postnatal maturation of the cerebellar cortex. May play a role in neurotransmission through regulation of glutaminase/GLS, an enzyme responsible for the production in neurons of the glutamate neurotransmitter. Alternatively, may regulate the localization of mitochondria within axons and dendrites. |
Protein Name | CaytaxinAtaxia Cayman Type ProteinBnip-2-HomologyBnip-H |
Cellular Localisation | Cell ProjectionAxonDendritePresynapseMitochondrionGrowth ConeCytoplasm |
Alternative Antibody Names | Anti-Caytaxin antibodyAnti-Ataxia Cayman Type Protein antibodyAnti-Bnip-2-Homology antibodyAnti-Bnip-H antibodyAnti-ATCAY antibodyAnti-KIAA1872 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance