| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ATCAY |
| Gene ID: | 85300 |
| Uniprot ID: | ATCAY_HUMAN |
| Immunogen Region: | 1-105 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human ATCAY (NP_149053.1). |
| Immunogen Sequence: | MGTTEATLRMENVDVKEEWQ DEDLPRPLPEETGVELLGSP VEDTSSPPNTLNFNGAHRKR KTLVAPEINISLDQSEGSLL SDDFLDTPDDLDINVDDIET PDETD |
| Post Translational Modifications | Cleaved by CASP3 and CASP7. The potential C-terminal product released by CASP3 cleavage may inhibit the ERK signaling pathway through MAP2K2. May be ubiquitinated by STUB1. |
| Function | Functions in the development of neural tissues, particularly the postnatal maturation of the cerebellar cortex. May play a role in neurotransmission through regulation of glutaminase/GLS, an enzyme responsible for the production in neurons of the glutamate neurotransmitter. Alternatively, may regulate the localization of mitochondria within axons and dendrites. |
| Protein Name | CaytaxinAtaxia Cayman Type ProteinBnip-2-HomologyBnip-H |
| Cellular Localisation | Cell ProjectionAxonDendritePresynapseMitochondrionGrowth ConeCytoplasm |
| Alternative Antibody Names | Anti-Caytaxin antibodyAnti-Ataxia Cayman Type Protein antibodyAnti-Bnip-2-Homology antibodyAnti-Bnip-H antibodyAnti-ATCAY antibodyAnti-KIAA1872 antibody |
Information sourced from Uniprot.org