• Western blot analysis of lysates from rat brain and mouse brain cells, using ARRDC3 Antibody. The lane on the right is blocked with the synthesized peptide.

Anti-ARRDC3 antibody (365-414 aa) (STJ91705)

SKU:
STJ91705

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Arrestin domain-containing protein 3 (365-414 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ARRDC3
Gene ID: 57561
Uniprot ID: ARRD3_HUMAN
Immunogen Region: 365-414 aa
Specificity: ARRDC3 Polyclonal Antibody detects endogenous levels of ARRDC3 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human ARRDC3 at the amino acid range 365-414
Function Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors. Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation. May recruit NEDD4 to ADRB2. Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes.
Protein Name Arrestin Domain-Containing Protein 3
Tbp-2-Like Inducible Membrane Protein
Tlimp
Cellular Localisation Cytoplasm
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Lysosome
Endosome
Early Endosome
Associated With Plasma Membrane
As Well As With Endosomes And Lysosomes During Endocytosis
Alternative Antibody Names Anti-Arrestin Domain-Containing Protein 3 antibody
Anti-Tbp-2-Like Inducible Membrane Protein antibody
Anti-Tlimp antibody
Anti-ARRDC3 antibody
Anti-KIAA1376 antibody

Information sourced from Uniprot.org

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