| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AQP10 (209-301) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AQP10 |
| Gene ID: |
89872 |
| Uniprot ID: |
AQP10_HUMAN |
| Immunogen Region: |
209-301 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 209-301 of human AQP10 (NP_536354.2). |
| Immunogen Sequence: |
CGIPLNPARDLGPRLFTYVA GWGPEVFSAGNGWWWVPVVA PLVGATVGTATYQLLVALHH PEGPEPAQDLVSAQHKASEL ETPASAQMLECKL |
| Tissue Specificity | Detected in epithelial cells on villi in the ileum, and also in stomach, jejunum, colon, rectum, white adipose tissue and placenta (at protein level). Expressed in duodenum and jejunum. Highest expression in absorptive epithelial cells at the tips of villi in the jejunum. Detected in subcutaneous adipose tissue. |
| Function | Isoform 1: Water channel that mediates water transport across cell membranes irrespective of the cytosolic pH. The channel is permeable to glycerol, especially when the cytosolic pH is acidified. Contributes to adipocyte water and glycerol permeability, and may thereby contribute to the utilization of glycerol derived from phospholipid degradation. May contribute to water transport in the intestine (Probable). Isoform 2: Water channel that mediates water transport across cell membranes, but that is not permeable to glycerol. |
| Protein Name | Aquaporin-10Aqp-10Aquaglyceroporin-10Small Intestine Aquaporin |
| Database Links | Reactome: R-HSA-432047 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinCell MembraneLipid DropletDetected Around Lipid Droplets |
| Alternative Antibody Names | Anti-Aquaporin-10 antibodyAnti-Aqp-10 antibodyAnti-Aquaglyceroporin-10 antibodyAnti-Small Intestine Aquaporin antibodyAnti-AQP10 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
