| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-APXL (C-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000. IHC: In paraffin embedded Human Kidney shows cytoplasm staining in PCT exclusively. Recommended concentration, 4-6µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | SHROOM2 |
| Gene ID: | 357 |
| Uniprot ID: | SHRM2_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_001640 |
| Immunogen Sequence: | KCLLDSLQPERGK |
| Function | May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution. |
| Protein Name | Protein Shroom2 Apical-Like Protein Protein Apxl |
| Cellular Localisation | Apical Cell Membrane Cell Junction Tight Junction Cytoplasm Cytoskeleton Associates With Cortical F-Actin |
| Alternative Antibody Names | Anti-Protein Shroom2 antibody Anti-Apical-Like Protein antibody Anti-Protein Apxl antibody Anti-SHROOM2 antibody Anti-APXL antibody |
Information sourced from Uniprot.org