Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit monoclonal antibody anti-Ankyrin Repeat Domain-Containing Protein 1 (1-130) is suitable for use in Western Blot research applications. |
Clonality: |
Monoclonal |
Clone ID: |
S4885RM |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
ANKRD1 |
Gene ID: |
27063 |
Uniprot ID: |
ANKR1_HUMAN |
Immunogen Region: |
1-130 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human ANKRD1 Rabbit PolymAb® (NP_055206.2). |
Immunogen Sequence: |
MMVLKVEELVTGKKNGNGEA GEFLPEDFRDGEYEAAVTLE KQEDLKTLLAHPVTLGEQQW KSEKQREAELKKKKLEQRSK LENLEDLEIIIQLKKRKKYR KTKVPVVKEPEPEIITEPVD VPTFLKAALE |
Tissue Specificity | Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells. |
Function | May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. |
Protein Name | Ankyrin Repeat Domain-Containing Protein 1Cardiac Ankyrin Repeat ProteinCytokine-Inducible Gene C-193 ProteinCytokine-Inducible Nuclear Protein |
Database Links | Reactome: R-HSA-1989781 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Ankyrin Repeat Domain-Containing Protein 1 antibodyAnti-Cardiac Ankyrin Repeat Protein antibodyAnti-Cytokine-Inducible Gene C-193 Protein antibodyAnti-Cytokine-Inducible Nuclear Protein antibodyAnti-ANKRD1 antibodyAnti-C193 antibodyAnti-CARP antibodyAnti-HA1A2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance