| Function | Broad-specificity nucleoside phosphate kinase involved in cellular nucleotide homeostasis by catalyzing nucleoside-phosphate interconversions. Similar to other adenylate kinases, preferentially catalyzes the phosphorylation of the nucleoside monophosphate AMP with ATP as phosphate donor to produce ADP. In vitro, can also catalyze the phosphorylation of CMP, dAMP and dCMP and use GTP as an alternate phosphate donor. Moreover, exhibits a diphosphate kinase activity, producing ATP, CTP, GTP, UTP, TTP, dATP, dCTP and dGTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donors. For this activity shows the following substrate preference CDP > UDP > ADP > TDP. |
| Protein Name | Adenylate Kinase 9Adenylate Kinase Domain-Containing Protein 1Adenylate Kinase Domain-Containing Protein 2 |
| Database Links | Reactome: R-HSA-499943 |
| Cellular Localisation | CytoplasmNucleusCell ProjectionCiliumFlagellum |
| Alternative Antibody Names | Anti-Adenylate Kinase 9 antibodyAnti-Adenylate Kinase Domain-Containing Protein 1 antibodyAnti-Adenylate Kinase Domain-Containing Protein 2 antibodyAnti-AK9 antibodyAnti-AKD1 antibodyAnti-AKD2 antibodyAnti-C6orf199 antibodyAnti-C6orf224 antibody |
Information sourced from Uniprot.org
