| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AK1 |
| Gene ID: | 203 |
| Uniprot ID: | KAD1_HUMAN |
| Immunogen Region: | 1-194 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human AK1 (NP_000467.1). |
| Immunogen Sequence: | MEEKLKKTKIIFVVGGPGSG KGTQCEKIVQKYGYTHLSTG DLLRSEVSSGSARGKKLSEI MEKGQLVPLETVLDMLRDAM VAKVNTSKGFLIDGYPREVQ QGEEFERRIGQPTLLLYVDA GPETMTQRLLKRGETSGRVD DNEETIKKRLETYYKATEPV IAFYEKRGIVRKVNAEGSVD SVFSQVCTHLDALK |
| Function | Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Also catalyzes at a very low rate the synthesis of thiamine triphosphate (ThTP) from thiamine diphosphate (ThDP) and ADP. |
| Protein Name | Adenylate Kinase Isoenzyme 1Ak 1 Atp-Amp Transphosphorylase 1Atp -Amp PhosphotransferaseAdenylate Monophosphate KinaseMyokinase |
| Database Links | Reactome: R-HSA-499943 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Adenylate Kinase Isoenzyme 1 antibodyAnti-Ak 1 antibodyAnti-Atp-Amp Transphosphorylase 1 antibodyAnti-Atp -Amp Phosphotransferase antibodyAnti-Adenylate Monophosphate Kinase antibodyAnti-Myokinase antibodyAnti-AK1 antibody |
Information sourced from Uniprot.org