• Western blot analysis of lysates from wild type (WT) and AIP knockout (KO) HeLa cells, using [KO Validated] AIP Rabbit polyclonal antibody (STJ11100845) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.

Anti-AIP antibody (1-330) (STJ11100845)

SKU:
STJ11100845

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-AIP (1-330) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AIP
Gene ID: 9049
Uniprot ID: AIP_HUMAN
Immunogen Region: 1-330
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human AIP (NP_003968.3).
Immunogen Sequence: MADIIARLREDGIQKRVIQE GRGELPDFQDGTKATFHYRT LHSDDEGTVLDDSRARGKPM ELIIGKKFKLPVWETIVCTM REGEIAQFLCDIKHVVLYPL VAKSLRNIAVGKDPLEGQRH CCGVAQMREHSSLGHADLDA LQQNPQPLIFHMEMLKVESP GTYQQDPWAMTDEEKAKAVP LIHQEGNRLYREGHVKEAAA KYYDAIACLKNLQMKEQPGS PEWIQLDQQITPLLLNYCQ
Tissue Specificity Widely expressed. Higher levels seen in the heart, placenta and skeletal muscle. Not expressed in the liver.
Function May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting. Cellular negative regulator of the hepatitis B virus (HBV) X protein.
Protein Name Ah Receptor-Interacting Protein
Aip
Aryl-Hydrocarbon Receptor-Interacting Protein
Hbv X-Associated Protein 2
Xap-2
Immunophilin Homolog Ara9
Database Links Reactome: R-HSA-8937144
Reactome: R-HSA-8950505
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Ah Receptor-Interacting Protein antibody
Anti-Aip antibody
Anti-Aryl-Hydrocarbon Receptor-Interacting Protein antibody
Anti-Hbv X-Associated Protein 2 antibody
Anti-Xap-2 antibody
Anti-Immunophilin Homolog Ara9 antibody
Anti-AIP antibody
Anti-XAP2 antibody

Information sourced from Uniprot.org

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