• Western blot of mouse spleen lysate showing specific immunolabeling of the ~17 kDa AIF1/Iba1 protein.
  • Immunofluoresence of FLAG-tagged AIF1 transfected COS cells showing AIF1 staining in red (STJA0003858, 1:50) and FLAG staining in green causing positive transfected cells to appear yellow. DNA is stained blue with DAPI.

Anti-AIF1/Iba1 antibody (Full Length) (STJA0003858)

SKU:
STJA0003858-100

£442.50
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Host: Rabbit
Applications: WB/ICC
Reactivity: Human/Mouse/Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-AIF1/Iba1 (Full Length) is suitable for use in Western Blot and Immunocytochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol.
Purification: Antigen affinity purified serum
Dilution Range: WB 1:1000
IHC
ICC 1:500-1:5000
IP
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AIF1
Gene ID: 199
Uniprot ID: AIF1_HUMAN
Immunogen Region: Full Length
Immunogen: Full-length human AIF1 expressed in and purified from E. coli
Post Translational Modifications Phosphorylated on serine residues.
Function Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Protein Name Allograft Inflammatory Factor 1
Aif-1
Ionized Calcium-Binding Adapter Molecule 1
Protein G1
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Projection
Ruffle Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Phagocytic Cup
Associated With The Actin Cytoskeleton At Membrane Ruffles And At Sites Of Phagocytosis
Alternative Antibody Names Anti-Allograft Inflammatory Factor 1 antibody
Anti-Aif-1 antibody
Anti-Ionized Calcium-Binding Adapter Molecule 1 antibody
Anti-Protein G1 antibody
Anti-AIF1 antibody
Anti-G1 antibody
Anti-IBA1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance