| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AGXT2 (42-300) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AGXT2 |
| Gene ID: |
64902 |
| Uniprot ID: |
AGT2_HUMAN |
| Immunogen Region: |
42-300 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 42-300 of human AGXT2 (NP_001293102.1). |
| Immunogen Sequence: |
LHTKPRMPPCDFMPERYQSL GYNRVLEIHKEHLSPVVTAY FQKPLLLHQGHMEWLFDAEG SRYLDFFSGIVTVSVGHCHP KVNAVAQKQLGRLWHTSTVF FHPPMHEYAEKLAALLPEPL KVIFLVNSGSEANELAMLMA RAHSNNIDIISFRGAYHGCS PYTLGLTNVGTYKMELPGGT GCQPTMCPDVFRGPWGGSHC RDSPVQTIRKCSCAPDCCQA KDQYIEQFKDTLSTSVAKS |
| Function | Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure. |
| Protein Name | Alanine--Glyoxylate Aminotransferase 2 - MitochondrialAgt 2(R-3-Amino-2-Methylpropionate--Pyruvate TransaminaseBeta-Alaat IiBeta-Alanine-Pyruvate AminotransferaseD-Aibat |
| Database Links | Reactome: R-HSA-389661Reactome: R-HSA-73621 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Alanine--Glyoxylate Aminotransferase 2 - Mitochondrial antibodyAnti-Agt 2 antibodyAnti-(R-3-Amino-2-Methylpropionate--Pyruvate Transaminase antibodyAnti-Beta-Alaat Ii antibodyAnti-Beta-Alanine-Pyruvate Aminotransferase antibodyAnti-D-Aibat antibodyAnti-AGXT2 antibodyAnti-AGT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
