• Western blot analysis of various lysates using AGRB2 Rabbit polyclonal antibody (STJ114258) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-AGRB2 antibody (700-800) (STJ114258)

SKU:
STJ114258

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-AGRB2 (700-800) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADGRB2
Gene ID: 576
Uniprot ID: AGRB2_HUMAN
Immunogen Region: 700-800
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 700-800 of human AGRB2 (NP_001281264.1).
Immunogen Sequence: DFIHLVGDALKAFQSSLIVT DNLVISIQREPVSAVSSDIT FPMRGRRGMKDWVRHSEDRL FLPKEVLSLSSPGKPATSGA AGSPGRGRGPGTVPPGPGHS H
Tissue Specificity Detected in cerebrospinal fluid (at protein level). Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines.
Post Translational Modifications Autoproteolytically processed at the GPS domain.this cleavage modulates receptor activity. Additionally, furin is involved in the cleavage at another site, in the middle of the extracellular domain, generating a soluble fragment. Glycosylated.
Function Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT-signaling pathway, a transcription factor, via the G-protein GNAZ. Involved in angiogenesis inhibition.
Protein Name Adhesion G Protein-Coupled Receptor B2
Brain-Specific Angiogenesis Inhibitor 2
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Secreted
Alternative Antibody Names Anti-Adhesion G Protein-Coupled Receptor B2 antibody
Anti-Brain-Specific Angiogenesis Inhibitor 2 antibody
Anti-ADGRB2 antibody
Anti-BAI2 antibody

Information sourced from Uniprot.org

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