Anti-ADCY3 antibody {Biotin} (STJ502066)


Current Stock:
Host: Rabbit
Applications: ELISA, IP, WB
Reactivity: Dog, Human, Mouse, Rat
Short Description: Rabbit polyclonal antibody anti-ADCY3 is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.68 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:50-1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: ADCY3
Gene ID: 109
Immunogen: Synthetic peptide generated against a sequence unique to PAC3 protein. All peptides were amidated before conjugation.
Tissue Specificity Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level). Expressed in brain, heart, kidney, liver, lung, pancreas islets, placenta, and skeletal muscle. Detected in testis.
Post Translational Modifications Sumoylated. Sumoylation is required for targeting ot olfactory cilia. N-glycosylated. Rapidly phosphorylated after stimulation by odorants or forskolin. Phosphorylation by CaMK2 at Ser-1076 down-regulates enzyme activity.
Function Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet.
Protein Name Adenylate Cyclase Type 3
Atp Pyrophosphate-Lyase 3
Adenylate Cyclase Type Iii
Adenylate Cyclase - Olfactive Type
Adenylyl Cyclase 3
Database Links Reactome: R-HSA-163359
Reactome: R-HSA-163615
Reactome: R-HSA-164378
Reactome: R-HSA-170660
Reactome: R-HSA-170670
Reactome: R-HSA-418555
Reactome: R-HSA-418594
Reactome: R-HSA-418597
Reactome: R-HSA-432040
Reactome: R-HSA-5610787
Reactome: R-HSA-9660821
Reactome: R-HSA-9664323
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Golgi Apparatus
Also Detected In The Cytoplasm
Close To Lipid Droplets
Alternative Antibody Names Anti-Adenylate Cyclase Type 3 antibody
Anti-Atp Pyrophosphate-Lyase 3 antibody
Anti-Adenylate Cyclase Type Iii antibody
Anti-Ac-Iii antibody
Anti-Adenylate Cyclase - Olfactive Type antibody
Anti-Adenylyl Cyclase 3 antibody
Anti-Ac3 antibody
Anti-ADCY3 antibody
Anti-KIAA0511 antibody

Information sourced from

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance