Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Adenylate cyclase type 10 (368-418 aa) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ADCY10 |
Gene ID: | 55811 |
Uniprot ID: | ADCYA_HUMAN |
Immunogen Region: | 368-418 aa |
Specificity: | This antibody detects endogenous levels of ADCYA at Human/Mouse/Rat |
Immunogen: | Synthesized peptide derived from the human ADCYA at the amino acid range 368-418 |
Post Translational Modifications | Cleavage may occur to generate the active 48 kDa form. |
Function | Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation. |
Protein Name | Adenylate Cyclase Type 10 Ah-Related Protein Adenylate Cyclase Homolog Germ Cell Soluble Adenylyl Cyclase Hsac Sac Testicular Soluble Adenylyl Cyclase |
Database Links | Reactome: R-HSA-5610787 |
Cellular Localisation | Cell Membrane Peripheral Membrane Protein Cytoplasmic Side Cytoplasm Cytoskeleton Perinuclear Region Nucleus Cell Projection Cilium Mitochondrion Distributed To Subcellular Compartments Containing Camp Targets Found As A Plasma Membrane-Associated Protein Protein Concentrated In The Perinuclear Region And Protein Colocalized With Actin Or Tubulin |
Alternative Antibody Names | Anti-Adenylate Cyclase Type 10 antibody Anti-Ah-Related Protein antibody Anti-Adenylate Cyclase Homolog antibody Anti-Germ Cell Soluble Adenylyl Cyclase antibody Anti-Hsac antibody Anti-Sac antibody Anti-Testicular Soluble Adenylyl Cyclase antibody Anti-ADCY10 antibody Anti-SAC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance