Post Translational Modifications | Cleavage may occur to generate the active 48 kDa form. |
Function | Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation. |
Protein Name | Adenylate Cyclase Type 10Ah-Related ProteinAdenylate Cyclase HomologGerm Cell Soluble Adenylyl CyclaseHsacSacTesticular Soluble Adenylyl Cyclase |
Database Links | Reactome: R-HSA-5610787 |
Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonPerinuclear RegionNucleusCell ProjectionCiliumMitochondrionDistributed To Subcellular Compartments Containing Camp TargetsFound As A Plasma Membrane-Associated ProteinProtein Concentrated In The Perinuclear Region And Protein Colocalized With Actin Or Tubulin |
Alternative Antibody Names | Anti-Adenylate Cyclase Type 10 antibodyAnti-Ah-Related Protein antibodyAnti-Adenylate Cyclase Homolog antibodyAnti-Germ Cell Soluble Adenylyl Cyclase antibodyAnti-Hsac antibodyAnti-Sac antibodyAnti-Testicular Soluble Adenylyl Cyclase antibodyAnti-ADCY10 antibodyAnti-SAC antibody |
Information sourced from Uniprot.org