| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Adenylate cyclase type 10 (368-418 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ADCY10 |
| Gene ID: |
55811 |
| Uniprot ID: |
ADCYA_HUMAN |
| Immunogen Region: |
368-418 aa |
| Specificity: |
This antibody detects endogenous levels of ADCYA at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human ADCYA at the amino acid range 368-418 |
| Post Translational Modifications | Cleavage may occur to generate the active 48 kDa form. |
| Function | Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation. |
| Protein Name | Adenylate Cyclase Type 10Ah-Related ProteinAdenylate Cyclase HomologGerm Cell Soluble Adenylyl CyclaseHsacSacTesticular Soluble Adenylyl Cyclase |
| Database Links | Reactome: R-HSA-5610787 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonPerinuclear RegionNucleusCell ProjectionCiliumMitochondrionDistributed To Subcellular Compartments Containing Camp TargetsFound As A Plasma Membrane-Associated ProteinProtein Concentrated In The Perinuclear Region And Protein Colocalized With Actin Or Tubulin |
| Alternative Antibody Names | Anti-Adenylate Cyclase Type 10 antibodyAnti-Ah-Related Protein antibodyAnti-Adenylate Cyclase Homolog antibodyAnti-Germ Cell Soluble Adenylyl Cyclase antibodyAnti-Hsac antibodyAnti-Sac antibodyAnti-Testicular Soluble Adenylyl Cyclase antibodyAnti-ADCY10 antibodyAnti-SAC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
