| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:2000-1:7000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
Adgre5 |
| Gene ID: |
26364 |
| Uniprot ID: |
AGRE5_MOUSE |
| Immunogen Region: |
24-415 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 24-415 of human ACAD8. (NP_055199.1). |
| Immunogen Sequence: |
VQTGHRSLTSCIDPSMGLNE EQKEFQKVAFDFAAREMAPN MAEWDQKELFPVDVMRKAAQ LGFGGVYIQTDVGGSGLSRL DTSVIFEALATGCTSTTAYI SIHNMCAWMIDSFGNEEQRH KFCPPLCTMEKFASYCLTEP GSGSDAASLLTSAKKQGDHY ILNGSKAFISGAGESDIYVV MCRTGGPGPKGISCIVVEKG TPGLSFGKKEKKVGWNSQPT RAVIFEDCAVPVANRIGSE |
| Tissue Specificity | Although predominantly expressed by cells of the immune system, expressed ubiquitously with particularly high levels of expression in the lung and the thymus gland. In the spleen, expression is detected on most myeloid cells and variable portions of T-cells, B-cells and NK cells. In the bone marrow, expressed in nearly all myeloid cells, whereas little if any expression is found on erythroid cells. |
| Post Translational Modifications | Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. |
| Function | Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration. |
| Protein Name | Adhesion G Protein-Coupled Receptor E5Leukocyte Antigen Cd97Cd Antigen Cd97 Cleaved Into - Adhesion G Protein-Coupled Receptor E5 Subunit Alpha - Adhesion G Protein-Coupled Receptor E5 Subunit Beta |
| Database Links | Reactome: R-MMU-373080Reactome: -MMU-6798695 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinAdhesion G Protein-Coupled Receptor E5 Subunit Alpha: SecretedExtracellular Space |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor E5 antibodyAnti-Leukocyte Antigen Cd97 antibodyAnti-Cd Antigen Cd97 Cleaved Into - Adhesion G Protein-Coupled Receptor E5 Subunit Alpha - Adhesion G Protein-Coupled Receptor E5 Subunit Beta antibodyAnti-Adgre5 antibodyAnti-Cd97 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
