Anti-ABCF1 antibody (121-205) (STJ11100291)

SKU:
STJ11100291

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ABCF1 (121-205) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ABCF1
Gene ID: 23
Uniprot ID: ABCF1_HUMAN
Immunogen Region: 121-205
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 121-205 of human ABCF1 (Q8NE71).
Immunogen Sequence: RGGKKTKGGNVFAALIQDQS EEEEEEEKHPPKPAKPEKNR INKAVSEEQQPALKGKKGKE EKSKGKAKPQNKFAALDNEE EDKEE
Tissue Specificity Ubiquitous.
Post Translational Modifications Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2 inhibits association of EIF2 with ribosomes.
Function Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis.
Protein Name Atp-Binding Cassette Sub-Family F Member 1
Atp-Binding Cassette 50
Tnf-Alpha-Stimulated Abc Protein
Database Links Reactome: R-HSA-382556
Cellular Localisation Isoform 2: Cytoplasm
Nucleus
Nucleoplasm
Nucleus Envelope
Alternative Antibody Names Anti-Atp-Binding Cassette Sub-Family F Member 1 antibody
Anti-Atp-Binding Cassette 50 antibody
Anti-Tnf-Alpha-Stimulated Abc Protein antibody
Anti-ABCF1 antibody
Anti-ABC50 antibody

Information sourced from Uniprot.org

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