Anti-ABCC1 antibody (110-190) (STJ190989)


Current Stock:
Host: Rabbit
Applications: WB, ELISA
Reactivity: Human, Rat, Mouse
Short Description: Rabbit polyclonal antibody anti-Multidrug Resistance-Associated Protein 1 (110-190) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS, 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ABCC1
Gene ID: 4363
Uniprot ID: MRP1_HUMAN
Immunogen Region: 110-190
Specificity: ABCC1 polyclonal antibody (Multidrug Resistance-Associated Protein 1) binds to endogenous Multidrug Resistance-Associated Protein 1 at the amino acid region 110-190.
Immunogen: Synthesized peptide derived from human protein at aa range 110-190
Function Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation. Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells.
Protein Name Multidrug Resistance-Associated Protein 1
Atp-Binding Cassette Sub-Family C Member 1
Glutathione-S-Conjugate-Translocating Atpase Abcc1
Leukotriene C(4 Transporter
Ltc4 Transporter
Database Links Reactome: R-HSA-189483
Reactome: R-HSA-196741
Reactome: R-HSA-2142691
Reactome: R-HSA-382556
Reactome: R-HSA-9707564
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Multidrug Resistance-Associated Protein 1 antibody
Anti-Atp-Binding Cassette Sub-Family C Member 1 antibody
Anti-Glutathione-S-Conjugate-Translocating Atpase Abcc1 antibody
Anti-Leukotriene C(4 Transporter antibody
Anti-Ltc4 Transporter antibody
Anti-ABCC1 antibody
Anti-MRP antibody
Anti-MRP1 antibody

Information sourced from

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