| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AASS |
| Gene ID: | 10157 |
| Uniprot ID: | AASS_HUMAN |
| Immunogen Region: | 180-400 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-400 of human AASS (NP_005754.2). |
| Immunogen Sequence: | MHIGMAHNYRNSSQAVQAVR DAGYEISLGLMPKSIGPLTF VFTGTGNVSKGAQAIFNELP CEYVEPHELKEVSQTGDLRK VYGTVLSRHHHLVRKTDAVY DPAEYDKHPERYISRFNTDI APYTTCLINGIYWEQNTPRL LTRQDAQSLLAPGKFSPAGV EGCPALPHKLVAICDISADT GGSIEFMTECTTIEHPFCMY DADQHIIHDSVEGSGILMCS I |
| Tissue Specificity | Expressed in all 16 tissues examined with highest expression in the liver. |
| Function | Bifunctional enzyme that catalyzes the first two steps in lysine degradation. |
| Protein Name | Alpha-Aminoadipic Semialdehyde Synthase - MitochondrialLkr/Sdh Includes - Lysine Ketoglutarate ReductaseLkrLor - Saccharopine DehydrogenaseSdh |
| Database Links | Reactome: R-HSA-71064 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Alpha-Aminoadipic Semialdehyde Synthase - Mitochondrial antibodyAnti-Lkr/Sdh Includes - Lysine Ketoglutarate Reductase antibodyAnti-Lkr antibodyAnti-Lor - Saccharopine Dehydrogenase antibodyAnti-Sdh antibodyAnti-AASS antibody |
Information sourced from Uniprot.org