| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | A4GNT |
| Gene ID: | 51146 |
| Uniprot ID: | A4GCT_HUMAN |
| Immunogen Region: | 1-340 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-340 of human A4GNT (NP_057245.1). |
| Immunogen Sequence: | MRKELQLSLSVTLLLVCGFL YQFTLKSSCLFCLPSFKSHQ GLEALLSHRRGIVFLETSER MEPPHLVSCSVESAAKIYPE WPVVFFMKGLTDSTPMPSNS TYPAFSFLSAIDNVFLFPLD MKRLLEDTPLFSWYNQINAS AERNWLHISSDASRLAIIWK YGGIYMDTDVISIRPIPEEN FLAAQASRYSSNGIFGFLPH HPFLWECMENFVEHYNSAIW GNQGPELMTRMLRVWCKLE |
| Tissue Specificity | Detected in stomach and pancreas. |
| Function | Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas. |
| Protein Name | Alpha-1 -4-N-AcetylglucosaminyltransferaseAlpha4gnt |
| Database Links | Reactome: R-HSA-913709 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Alpha-1 -4-N-Acetylglucosaminyltransferase antibodyAnti-Alpha4gnt antibodyAnti-A4GNT antibody |
Information sourced from Uniprot.org