Anti-5HT1A antibody (200-250) {Biotin} (STJ500001)


Current Stock:
Host: Rabbit
Applications: ELISA, IP, WB
Reactivity: Human, Mouse, Rat
Short Description: Rabbit polyclonal antibody anti-5HT1A (200-250) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5-1.5 µg/µl
Dilution Range: WB: 1:2, 500-1:5, 000
DB: 1:50, 000
ELISA: 1:50, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Htr1a
Gene ID: 24473
Uniprot ID: 5HT1A_RAT
Immunogen Region: 200-250
Immunogen: Synthetic peptide corresponding to amino acids within region 200-250 on rat 5-hydroxytryptamine receptor 1A protein.
Tissue Specificity Detected in hypothalamus, mesencephalon, amygdala, medulla, thalamus, septum and hippocampus.
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
Protein Name 5-Hydroxytryptamine Receptor 1a
Serotonin Receptor 1a
Database Links Reactome: R-RNO-390666
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Alternative Antibody Names Anti-5-Hydroxytryptamine Receptor 1a antibody
Anti-5-Ht-1a antibody
Anti-5-Ht1a antibody
Anti-Serotonin Receptor 1a antibody
Anti-Htr1a antibody
Anti-5ht1a antibody

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