• Dot-blot analysis of 5-Hydroxymethylcytosine (5-hmC) , 5-Methylcytosine (5mC) and unmodified adenosine using 5-Hydroxymethylcytosine/5-hmC antibody (STJ11103938) at 1:500/1:2000 dilution. NA NA m5C 1- 5 NA CAGTAACTGTGGTCCGGTAACTGACTTGCA3 NA NA NA m5C 2- 5 NA CAGTAACTGTGGTC/i5MedC/GGTAACTGACTTGCA3 NA

Anti-5-Hydroxymethylcytosine/5-hmC antibody (STJ11103938)

SKU:
STJ11103938

£116.50 - £543.50
Current Stock:
Host: Rabbit
Reactivity: Human/Mouse/Rat/Other
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-5-Hydroxymethylcytosine/5-hmC is suitable for use in research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: DB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunogen: Chemical compounds corresponding to 5-hydroxymethylcytidine/hm5C.
Background In mammalian genomes, 5-mC can be enzymatically oxidized to 5-hmC (5-hydroxymethylcytosine). This modification is suggested to be an intermediate between methylation and demethylation of the genome. Occupancy of 5-hmC correlates with inactive or non-productive promoters (PMID: 21925312). 5-hmC pattern is different from 5-methylcytosine (5-mC) in many instances (PMID: 21610077).

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance