| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Adenylate Cyclase 10 Positive Control for STJ502868 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Adcy10 |
| Gene ID: |
271639 |
| Uniprot ID: |
ADCYA_MOUSE |
| Specificity: |
This is positive control is recommended for use in combination with Adenylate Cyclase 10 antibody STJ502868. |
| Tissue Specificity | Expressed in testis. |
| Function | Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation. |
| Peptide Name | Adenylate Cyclase Type 10Germ Cell Soluble Adenylyl CyclaseSacTesticular Soluble Adenylyl Cyclase |
| Database Links | Reactome: R-MMU-5610787 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonPerinuclear RegionNucleusCell ProjectionCiliumMitochondrionDistributed To Subcellular Compartments Containing Camp TargetsFound As A Plasma Membrane-Associated ProteinProtein Concentrated In The Perinuclear Region And Protein Colocalized With Actin Or Tubulin |
| Alternative Peptide Names | Adenylate Cyclase Type 10 proteinGerm Cell Soluble Adenylyl Cyclase proteinSac proteinTesticular Soluble Adenylyl Cyclase proteinAdcy10 proteinSac proteinSacy protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
