| Applications: |
Immunodepletion/Immunocompetition |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Adenylate Cyclase 10 Blocking Peptide for STJ502868 is synthetically produced from the 200-250 sequence and is suitable for use in western blot applications. |
| Formulation: |
Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Adcy10 |
| Gene ID: |
271639 |
| Uniprot ID: |
ADCYA_MOUSE |
| Immunogen Region: |
200-250 |
| Specificity: |
This blocking peptide is recommended for use in combination with Adenylate Cyclase 10 antibody, STJ502868 |
| Immunogen: |
Synthetic peptide taken within amino acid region 200-250 on mouse Adenylate Cyclase type 10 protein. |
| Tissue Specificity | Expressed in testis. |
| Function | Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. Involved in ciliary beat regulation. |
| Peptide Name | Adenylate Cyclase Type 10Germ Cell Soluble Adenylyl CyclaseSacTesticular Soluble Adenylyl Cyclase |
| Database Links | Reactome: R-MMU-5610787 |
| Cellular Localisation | Cell MembranePeripheral Membrane ProteinCytoplasmic SideCytoplasmCytoskeletonPerinuclear RegionNucleusCell ProjectionCiliumMitochondrionDistributed To Subcellular Compartments Containing Camp TargetsFound As A Plasma Membrane-Associated ProteinProtein Concentrated In The Perinuclear Region And Protein Colocalized With Actin Or Tubulin |
| Alternative Peptide Names | Adenylate Cyclase Type 10 proteinGerm Cell Soluble Adenylyl Cyclase proteinSac proteinTesticular Soluble Adenylyl Cyclase proteinAdcy10 proteinSac proteinSacy protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
