Mouse SFRP1 (Secreted Frizzled Related Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018508)

Mouse SFRP1 (Secreted Frizzled Related Protein 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018508)

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STJE0018508
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 13.3pg/mL
Detection Limit: 31.2-2000pg/mL
Short Description : This SFRP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse serum, plasma, tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Sfrp1
Gene ID: 20377
Uniprot ID: SFRP1_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Highly expressed in kidney and embryonic heart. Also highly expressed in the eye, where it is principally localized to the ciliary body and the lens epithelium. Weaker expression in heart, lung and brain. In the brain, is expressed exclusively in the choroid plexus.
Post Translational Modifications
Function Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels. Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase. In kidney development, inhibits tubule formation and bud growth in metanephroi. Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Protein Name Secreted Frizzled-Related Protein 1
Sfrp-1
Database Links
Cellular Localisation Secreted
Cell Membrane Or Extracellular Matrix-Associated
Released By Heparin-Binding
Alternative ELISA Names Secreted Frizzled-Related Protein 1 ELISA kit
Sfrp-1 ELISA kit
Sfrp1 ELISA kit
output

Information sourced from Uniprot.org

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