| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of 20 mM PB, 800 mM NaCl, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <1 EU/Mu g of the protein by LAL method. |
| Immunoreactivity: | Measured in a cell proliferation assay using Balb3T3 mouse fibroblast cells. The ED50 for this effect is 0.52-2.06 ng/mL, corresponding to a specific activity of 4.85×105~1.92×106 units/mg. |
| Gene Symbol: | Fgf6 |
| Gene ID: | 14177 |
| Uniprot ID: | FGF6_MOUSE |
| Immunogen Region: | Ser38-Ile208 |
| Immunogen: | Recombinant Mouse FGF-6 Protein is produced by E.coli expression system. The target protein is expressed with sequence (Ser38-Ile208) of Mouse FGF-6 (Accession #NP_034334.1) fused with No-Tag. |
| Immunogen Sequence: | VGSEVSDKRTCVSLTTQRLP VSRIKTYTITEGSLRAVIFI TKRGLKVCADPQATWVRDVV RSMDRKSNTRNNMIQTKPTG TQQSTNTAVTLTG |
| Tissue Specificity | Embryos, adult muscles and adult testis. |
| Function | Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration. |
| Protein Name | Fibroblast Growth Factor 6Fgf-6Heparin Secretory-Transforming Protein 2Hst-2Hstf-2Heparin-Binding Growth Factor 6Hbgf-6 |
| Database Links | Reactome: R-MMU-109704Reactome: -MMU-1257604Reactome: -MMU-190322Reactome: -MMU-190373Reactome: -MMU-190375Reactome: -MMU-5654219Reactome: -MMU-5654221Reactome: -MMU-5654228Reactome: -MMU-5654687Reactome: -MMU-5654688Reactome: -MMU-5654689Reactome: -MMU-5654693Reactome: -MMU-5654695Reactome: -MMU-5654699Reactome: -MMU-5654700Reactome: -MMU-5654712Reactome: -MMU-5654719Reactome: -MMU-5654720Reactome: -MMU-5654726Reactome: -MMU-5654727Reactome: -MMU-5654733Reactome: -MMU-5673001Reactome: -MMU-6811558 |
| Cellular Localisation | SecretedExtracellular Space |
| Alternative Protein Names | Fibroblast Growth Factor 6 proteinFgf-6 proteinHeparin Secretory-Transforming Protein 2 proteinHst-2 proteinHstf-2 proteinHeparin-Binding Growth Factor 6 proteinHbgf-6 proteinFgf6 proteinFgf-6 proteinHstf2 protein |
Information sourced from Uniprot.org