Tissue Specificity | |
Post Translational Modifications | Phosphorylation at Ser-251, Ser-282 and Ser-285 by CaMK2/CaMKII in response to calcium signaling decreases affinity for DNA: an increasing number of phosphoserines causes DNA-binding to become progressively weaker. Sumoylated on Lys-15 and Lys-227, preferentially with SUMO2.which inhibits transcriptional activity. Ubiquitinated.which induces proteasomal degradation. |
Function | Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion. |
Protein Name | Protein C-Ets-1P54 |
Database Links | Reactome: R-MMU-2559585 |
Cellular Localisation | NucleusCytoplasm |
Alternative ELISA Names | Protein C-Ets-1 ELISA kitP54 ELISA kitEts1 ELISA kitEts-1 ELISA kit |
output | |
Information sourced from Uniprot.org