Mouse EAAT2 (Excitatory Amino Acid Transporter 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014930)

Mouse EAAT2 (Excitatory Amino Acid Transporter 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014930)

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STJE0014930
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Applications: ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.039ng/mL
Detection Limit: 0.156-10ng/mL
Short Description : This EAAT2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse tissue homogenates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Slc1a2
Gene ID: 20511
Uniprot ID: EAA2_MOUSE
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Detected in brain. Detected in embryonic forebrain, especially in globus pallidus, perirhinal cortex, lateral hypothalamus, hippocampus, and on fimbria and axonal pathways connecting the neocortex, basal ganglia and thalamus (at protein level). Isoform GLT1 is expressed in the brain. Isoforms GLT-1A and GLT-1B are expressed in the liver.
Post Translational Modifications Glycosylated. Palmitoylation at Cys-38 is not required for correct subcellular localization, but is important for glutamate uptake activity.
Function Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport.this avoids the accumulation of negative charges due to aspartate and Na(+) symport. Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate.
Protein Name Excitatory Amino Acid Transporter 2
Glt-1
Sodium-Dependent Glutamate/Aspartate Transporter 2
Solute Carrier Family 1 Member 2
Database Links Reactome: R-MMU-210455
Reactome: -MMU-210500
Reactome: -MMU-425393
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative ELISA Names Excitatory Amino Acid Transporter 2 ELISA kit
Glt-1 ELISA kit
Sodium-Dependent Glutamate/Aspartate Transporter 2 ELISA kit
Solute Carrier Family 1 Member 2 ELISA kit
Slc1a2 ELISA kit
Eaat2 ELISA kit
Glt1 ELISA kit
output

Information sourced from Uniprot.org

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