Tissue Specificity | Expressed in neuronal tissues, retina, spleen, and pancreatic islet cells. |
Post Translational Modifications | |
Function | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel. They are however insensitive to dihydropyridines (DHP). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing. |
Protein Name | Voltage-Dependent R-Type Calcium Channel Subunit Alpha-1eBrain Calcium Channel IiBiiCalcium Channel - L Type - Alpha-1 Polypeptide - Isoform 6Voltage-Gated Calcium Channel Subunit Alpha Cav2.3 |
Database Links | |
Cellular Localisation | MembraneMulti-Pass Membrane Protein |
Alternative ELISA Names | Voltage-Dependent R-Type Calcium Channel Subunit Alpha-1e ELISA kitBrain Calcium Channel Ii ELISA kitBii ELISA kitCalcium Channel - L Type - Alpha-1 Polypeptide - Isoform 6 ELISA kitVoltage-Gated Calcium Channel Subunit Alpha Cav2.3 ELISA kitCacna1e ELISA kitCach6 ELISA kitCacnl1a6 ELISA kitCchra1 ELISA kit |
output | |
Information sourced from Uniprot.org