| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.1 EU/Mu g |
| Gene Symbol: | Lrpap1 |
| Gene ID: | 16976 |
| Uniprot ID: | AMRP_MOUSE |
| Immunogen Region: | Gln29-Leu360 |
| Immunogen: | Recombinant Mouse Alpha-2-MRAP/LRPAP1 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln29-Leu360) of mouse Alpha-2-MRAP/LRPAP1 (Accession #NP_038615.2) fused with a 6×His tag at the C-terminus. |
| Immunogen Sequence: | QPIAGHGGKYSREKNEPEMA AKRESGEEFRMEKLNQLWEK AKRLHLSPVRLAELHSDLKI QERDELNWKKLKVEGLDKDG EKEAKLIHNLNVILARYGLD GRKDAQMVHSNALNEDTQDE LGDPRLEKLWHKAKTSGKFS SEELDKLWREFLHYKEKIQE YNVLLDTLSRAEEGYENLLS PSDMAHIKSDTLISKHSELK DRLRSINQGLDRLRKVSHQG YGSTTEFEEPRVIDLWDLA |
| Post Translational Modifications | N-glycosylated. |
| Function | Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway. |
| Protein Name | Alpha-2-Macroglobulin Receptor-Associated ProteinAlpha-2-MrapHeparin-Binding Protein 44Hbp-44Low Density Lipoprotein Receptor-Related Protein-Associated Protein 1Rap |
| Cellular Localisation | Rough Endoplasmic Reticulum LumenEndoplasmic Reticulum-Golgi Intermediate Compartment LumenGolgi ApparatusCis-Golgi NetworkGolgi Apparatus LumenEndosome LumenCell SurfaceMay Be Associated With Receptors At The Cell Surface |
| Alternative Protein Names | Alpha-2-Macroglobulin Receptor-Associated Protein proteinAlpha-2-Mrap proteinHeparin-Binding Protein 44 proteinHbp-44 proteinLow Density Lipoprotein Receptor-Related Protein-Associated Protein 1 proteinRap proteinLrpap1 protein |
Information sourced from Uniprot.org