Human USP47 protein (Recombinant) (N-His) (STJP011024)

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STJP011024
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human USP47-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: USP47
Gene ID: 55031
Uniprot ID: UBP47_HUMAN
Immunogen Region: Phe1034-Asp1319
Immunogen: Homo sapiens (Human)
Function Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level.
Protein Name Ubiquitin Carboxyl-Terminal Hydrolase 47
Deubiquitinating Enzyme 47
Ubiquitin Thioesterase 47
Ubiquitin-Specific-Processing Protease 47
Database Links Reactome: R-HSA-5689880
Cellular Localisation Cytoplasm
Alternative Protein Names Ubiquitin Carboxyl-Terminal Hydrolase 47 protein
Deubiquitinating Enzyme 47 protein
Ubiquitin Thioesterase 47 protein
Ubiquitin-Specific-Processing Protease 47 protein
USP47 protein

Information sourced from Uniprot.org

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