Human TMOD1 protein (Recombinant) (N-His) (STJP009610)

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STJP009610
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human TMOD1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: TMOD1
Gene ID: 7111
Uniprot ID: TMOD1_HUMAN
Immunogen Region: Gly160-Gly349
Immunogen: Homo sapiens (Human)
Function Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
Protein Name Tropomodulin-1
Erythrocyte Tropomodulin
E-Tmod
Database Links Reactome: R-HSA-390522
Cellular Localisation Cytoplasm
Cytoskeleton
In Myofibrils With Sarcomeric Structure
Localizes To The Pointed End Of Actin Thin Filaments
Alternative Protein Names Tropomodulin-1 protein
Erythrocyte Tropomodulin protein
E-Tmod protein
TMOD1 protein
D9S57E protein
TMOD protein

Information sourced from Uniprot.org