Function | Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus. |
Protein Name | Tropomodulin-1Erythrocyte TropomodulinE-Tmod |
Database Links | Reactome: R-HSA-390522 |
Cellular Localisation | CytoplasmCytoskeletonIn Myofibrils With Sarcomeric StructureLocalizes To The Pointed End Of Actin Thin Filaments |
Alternative Protein Names | Tropomodulin-1 proteinErythrocyte Tropomodulin proteinE-Tmod proteinTMOD1 proteinD9S57E proteinTMOD protein |
Information sourced from Uniprot.org