Name: Human SRGN protein (Recombinant) (N-His) (STJP003941)
SKU: STJP003941
Availability: InStock

Human SRGN protein (Recombinant) (N-His) (STJP003941)

SKU:

STJP003941

£328.50 - £1,437.50

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human SRGN-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.
Protein Name	Serglycin Hematopoietic Proteoglycan Core Protein Platelet Proteoglycan Core Protein P.pg Secretory Granule Proteoglycan Core Protein
Database Links	Reactome: R-HSA-114608
Cellular Localisation	Cytoplasmic Granule Cytolytic Granule Secreted Extracellular Space Golgi Apparatus Found In Mast Cell Granules And In Cytoplasmic Granules Of Cytolytic T Lymphocytes From Where It Is Secreted Upon Cell Activation Secreted Constitutively By Endothelial Cells And Macrophages Located To Golgi Apparatus During Neutrophil Differentiation
Alternative Protein Names	Serglycin protein Hematopoietic Proteoglycan Core Protein protein Platelet Proteoglycan Core Protein protein P.pg protein Secretory Granule Proteoglycan Core Protein protein SRGN protein PRG protein PRG1 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP005172	Human COL10A1, N-His protein (Recombinant) (N-His) (STJP005172)	E. coli
STJP004723	Human WAS protein (Recombinant) (N-His) (STJP004723)	E. coli
STJP003710	Human ISG15 protein (Recombinant) (N-His) (STJP003710)	E. coli
STJP003704	Human HMGN1 protein (Recombinant) (N-His) (STJP003704)	E. coli
STJP003719	Human HMGN2 protein (Recombinant) (N-His) (STJP003719)	E. coli

Human SRGN protein (Recombinant) (N-His) (STJP003941)

General Information