| Tissue Specificity | Widely expressed. |
| Post Translational Modifications | |
| Function | Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2), catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. For most substrates, PLA1 activity is much higher than PLA2 activity. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE), which serves as precursor for N-acylethanolamines (NAEs). Promotes keratinocyte differentiation via activation of TGM1. |
| Protein Name | Phospholipase A And Acyltransferase 4 Hras-Like Suppressor 4Hrsl4Rar-Responsive Protein Tig3Retinoic Acid Receptor Responder Protein 3Retinoid-Inducible Gene 1 ProteinTazarotene-Induced Gene 3 Protein |
| Database Links | Reactome: R-HSA-1482839 |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative ELISA Names | Phospholipase A And Acyltransferase 4 ELISA kitHras-Like Suppressor 4 ELISA kitHrsl4 ELISA kitRar-Responsive Protein Tig3 ELISA kitRetinoic Acid Receptor Responder Protein 3 ELISA kitRetinoid-Inducible Gene 1 Protein ELISA kitTazarotene-Induced Gene 3 Protein ELISA kitPLAAT4 ELISA kitRARRES3 ELISA kitRIG1 ELISA kitTIG3 ELISA kit |
| output | |
Information sourced from Uniprot.org
